Diabetes circa 1800

As Rees investigates murders, he invariably meets people who are ill. Illness and death was a constant companion. Illnesses: measles, mumps, diphtheria carried off infants and children; about one in five. Tuberculosis was epidemic. Women succumbed to childbirth. Simple accidents caused death, if not by the accident itself by sepsis.

Diseases we think of as modern, such as cancer or diabetes were present but not identified by name.

How do we know diabetes existed. About 3000 years ago the Egyptians described an illness with excessive thirst, urination and weight loss, the symptoms of Type I diabetes. In India they discovered they could use ants to detect the disease because the ants were drawn to the sweetness. And the Greeks called the disease diabetes mellitus ; diabetes for siphon or pass through and mellitus for sweet.

Early treatments included a diet of whole grains, milk and starchy foods, rancid animal meat, veal and mutton, green vegetables. Other treatments recommended exercising, reducing stress, wearing flannel – seriously. As one might expect, the true causes of Diabetes and possible treatments were not identified until modern times. In 1889, Joseph von Mering and Oskar Minkowski found that removing the pancreas from dogs led them to develop diabetes. In 1910 Sir Edward Albert Sharpey-Schafer named the missing chemical, without which the body could not survive, insulin. That means island because the cells in the islets of Langerhans in the pancreas produce it.

The first human subject took an insulin injection in 1922. So, although this illness has been with us a long time, its identification and the treatment is recent.

Why am I so interested in diabetes? Read Simply Dead and find out.